PUBLISHED INFORMATION

As the field of meniscal allograft transplantation grows so to does the research in this area.

Research from University Hospital Coventry & Warwickshire as well as other international centres is shared in this section.

Meniscal Transplant Recent research papers 2019 onward
University Hospital Coventry and Warwickshire NHS Trust, UK

Bone bridge technique for lateral meniscal allograft transplantation: no difference in clinical outcome compared to the soft tissue technique.

Bhattacharyya R, Krishnan H, Bausch N, Pilarski A, McGoldrick N, Thompson P, Metcalfe A, Spalding T. Knee Surg Sports Traumatol Arthrosc. 2023 Oct;31(10):4162-4170. doi: 10.1007/s00167-023-07443-7. Epub 2023 May 8.PMID: 37154910

RESULTS: One-hundred and twelve patients following lateral meniscal transplants were included, 31 in the BB group and 81 in the ST historical control group, with no differences in demographics between both groups. …There were 3 failures (9.6%) in the BB group v 2 …

Patient-reported outcome and survival following meniscal allograft transplantation : an international case series.

Barlow T, Coco V, Shivji F, Grassi A, Asplin L, Thompson P, Metcalfe A, Zaffagnini S, Spalding T. Bone Joint J. 2022 Jun;104-B(6):657-662. doi: 10.1302/0301-620X.104B6.BJJ-2021-0944.R2.PMID: 35638216

AIMS: Meniscal allograft transplantation (MAT) for patients with symptomatic meniscal loss has demonstrated good clinical results and survivorship. …

Extrusion, meniscal signal change, loss of shape, synovitis and bone marrow oedema are reliable scoring parameters to assess MRI appearance post meniscal transplant.

Damasena I, Onggo JR, Asplin L, Hutchinson C, Shah R, Spalding T. Knee Surg Sports Traumatol Arthrosc. 2022 May;30(5):1527-1534. doi: 10.1007/s00167-021-06720-7. Epub 2021 Aug 30.PMID: 34459933

PURPOSE: Meniscal allograft transplantation (MAT) has shown good promise in restoring normal knee joint biomechanics in a meniscal deficient patient. …All MAT were performed with soft tissue fixation technique. MRI was performed at 12 months post-transpl …

Meniscal allograft transplantation after meniscectomy: clinical effectiveness and cost-effectiveness.

Waugh N, Mistry H, Metcalfe A, Loveman E, Colquitt J, Royle P, Smith NA, Spalding T. Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):1825-1839. doi: 10.1007/s00167-019-05504-4. Epub 2019 Apr 13.PMID: 30982109 Free PMC article.

PURPOSE: To assess the clinical effectiveness and cost-effectiveness of meniscal allograft transplantation (MAT) after meniscal injury and subsequent meniscectomy. …RESULTS: There is considerable evidence from observational studies, of improvement in sympto …

Higher survivorship following meniscal allograft transplantation in less worn knees justifies earlier referral for symptomatic patients: experience from 240 patients.

Bloch B, Asplin L, Smith N, Thompson P, Spalding T.Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):1891-1899. doi: 10.1007/s00167-019-05459-6. Epub 2019 Mar 21.PMID: 30900033

PURPOSE: To analyse the clinical outcome and survivorship of meniscal allograft transplantation (MAT), performed in a single unit, specifically to assess the impact of concomitant operations and the influence of articular cartilage lesions on outcome. …Overall 27% …

Meniscal allograft transplantation in the paediatric population: early referral is justified.

Middleton S, Asplin L, Stevenson C, Thompson P, Spalding T.Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):1908-1913. doi: 10.1007/s00167-019-05437-y. Epub 2019 Feb 28.PMID: 30820601

PURPOSE: The need for meniscal allograft transplantation (MAT) in children is rare, and as a result, there is a paucity of evidence detailing survivorship and clinical outcome. …No patients developed a superficial or deep infection. CONCLUSION: Meniscal all …

Research Work from University Hospital Coventry and Warwickshire

Smith, NA., Parsons, N., Wright, D., Hutchinson, C., Metcalfe, A., Thompson, P., Costa, M. L., & Spalding, T. A pilot randomized trial of meniscal allograft transplantation versus personalized physiotherapy for patients with a symptomatic meniscal deficient knee compartment. Bone Joint J, 2018, 100-B(1), 56-63.

https://www.ncbi.nlm.nih.gov/pubmed/?term=A+pilot+randomized+trial+of+meniscal+allograft+transplantation+versus+personalized+physiotherapy+for+patients+with+a+symptomatic+meniscal+deficient+knee+compartment.

 

Smith, NA., Parsons, N., Wright, D., Hutchinson, C., Metcalfe, A., Thompson, P., Costa, M. L., & Spalding, T. Infographic: Meniscal transplantation is beneficial at one year. Bone Joint J, 2018, 100-B(1), 64-65.

http://bjj.boneandjoint.org.uk/content/100-B/1/64.long

 

Parkinson, B., Smith, NA., Asplin, L., Thompson, P., Spalding, T. Factors Predicting Meniscal Allograft Transplantation Failure, Orthopaedic Journal of Sports Medicine, 2016 4(8)

https://www.ncbi.nlm.nih.gov/pubmed/?term=Predicting+Meniscal+Allograft+Transplantation+Failure

 

Spalding, T., Parkinson, B., Milner, R., Smith, NA. Current Status of Meniscal Reconstruction, Journal of Trauma and Orthopaedics. 2016 4(1)

https://www.meniscaltransplant.com/CurrentStatusofMeniscalReconstruction.pdf

 

Spalding, T., Parkinson, B., Smith, NA., Verdonk, P. Arthroscopic Meniscal Allograft Transplantation With Soft Tissue Fixation Through Bone Tunnels, Arthroscopy Techniques. 2015, 4(5), e559–e563

https://www.ncbi.nlm.nih.gov/pubmed/26900554

 

Smith, NA., Costa, M., Spalding, T. Meniscal allograft transplantation: Rationale for treatment. Bone and Joint Journal. 2015, 97-B(5), 590-94

https://www.ncbi.nlm.nih.gov/pubmed/?term=Meniscal+allograft+transplantation%3A+Rationale+for+treatment

 

Smith, NA., Achten, J., Parsons, N., Wright, D., Parkinson, B., Hutchinson, CE., Thompson, P., Costa, M., Spalding, T. Meniscal Transplantation and Its Effect on Osteoarthritis Risk – an abridged protocol for the MeTEOR study. Bone and Joint Research. 2015, 4(6), 93-8

https://www.ncbi.nlm.nih.gov/pubmed/?term=Meniscal+Transplantation+and+Its+Effect+on+Osteoarthritis+Risk+%E2%80%93+an+abridged+protocol+for+the+MeTEOR+study

 

Smith, NA., Parkinson, B., Hutchinson, CE., Costa, M., Spalding, T. Is meniscal allograft transplantation chondroprotective? A systematic review. Knee Surgery, Sports Traumatology, Arthroscopy. 2015, 24(9) 2923-35

https://www.ncbi.nlm.nih.gov/pubmed/25786823

 

Smith, NA., MacKay, ND., Costa, M., Spalding, T. Meniscal allograft transplantation in a symptomatic meniscal deficient knee: a systematic review. Knee Surgery, Sports Traumatology, Arthroscopy. 2015, 23(1), 270-9

https://www.ncbi.nlm.nih.gov/pubmed/?term=Meniscal+allograft+transplantation+in+a+symptomatic+meniscal+deficient+knee%3A+a+systematic+review.

Other Recent Research

Lee DW, Park JH, Chung KS, Ha JK, Kim JG. Arthroscopic Medial Meniscal Allograft Transplantation with Modified Bone Plug Technique. Arthrosc Tech. 2017
Aug 28;6(4)
https://www.ncbi.nlm.nih.gov/pubmed/29354454

 

Woodmass JM, Johnson NR, Levy BA, Stuart MJ, Krych AJ. Lateral Meniscus Allograft Transplantation: The Bone Plug Technique. Arthrosc Tech. 2017 Aug 7;6(4)
https://www.ncbi.nlm.nih.gov/pubmed/29354420

 

Smith NA, Parsons N, Wright D, Hutchinson C, Metcalfe A, Thompson P, Costa ML, Spalding T. A pilot randomized trial of meniscal allograft transplantation versus personalized physiotherapy for patients with a symptomatic meniscal deficient knee compartment. Bone Joint J. 2018 Jan;100-B(1):56-63
https://www.ncbi.nlm.nih.gov/pubmed/29305451

 

Saltzman BM, Meyer MA, Leroux TS, Gilelis ME, Debot M, Yanke AB, Cole BJ. The
Influence of Full-Thickness Chondral Defects on Outcomes Following Meniscal Allograft Transplantation: A Comparative Study. Arthroscopy. 2017 Nov 2. pii:
S0749-8063(17)31109-X.
https://www.ncbi.nlm.nih.gov/pubmed/29103840

 

Chaudhry ZS, Fram B, Henn RF 3rd, Sherman SL, Hammoud S. The 50 Most-Cited Articles in Meniscal Allograft Transplantation Research: A Bibliometric Analysis.
Cartilage. 2017 Dec
Monllau JC, Ibañez M, Masferrer-Pino A, Gelber PE, Erquicia JI, Pelfort X. Lateral Capsular Fixation: An Implant-Free Technique to Prevent Meniscal Allograft Extrusion. Arthrosc Tech. 2017 Mar 6;6(2):e269-e274.
https://www.ncbi.nlm.nih.gov/pubmed/28580241

 

Bin SI, Nha KW, Cheong JY, Shin YS. Midterm and Long-term Results of Medial Versus Lateral Meniscal Allograft Transplantation: A Meta-analysis. Am J Sports
Med. 2017 Jun
https://www.ncbi.nlm.nih.gov/pubmed/?term=.+Midterm+and+Long-term+Results+of+Medial+Versus+Lateral+Meniscal+Allograft+Transplantation%3A+A+Meta-analysis

 

Roberson TA, Wyland DJ. Meniscal Allograft Transplantation With Soft Tissue in
Bone Socket Fixation: Arthroscopic Technique With Technical Pearls. Arthrosc
Tech. 2017 Apr 24;6(2)
https://www.ncbi.nlm.nih.gov/pubmed/?term=Meniscal+Allograft+Transplantation+With+Soft+Tissue+in+Bone+Socket+Fixation%3A+Arthroscopic+Technique+With+Technical+Pearls

 

Lee BS, Bin SI, Kim JM, Kim WK, Choi JW. Survivorship After Meniscal Allograft Transplantation According to Articular Cartilage Status. Am J Sports
Med. 2017 Apr;45(5):1095-1101.
https://www.ncbi.nlm.nih.gov/pubmed/?term=.+Survivorship+After+Meniscal+Allograft+Transplantation+According+to+Articular+Cartilage+Status